Host-Pathogen Interaction Laboratory
© 2015 - 2016 Uzonna (Created by F. Khadem)
2015 1 . Mou,   Z.,      Li      J.,      Boussoffara      T.,   Kishi   H.,   Hamana   H.,   Ezzati      P.,      Hu      C.,      Yi      W.,      Liu      D.,      Khadem      F.,      Okwor     I.,      Jia      P.,      Shitaoka   K.,   Wang      S.,      Ndao      M.,   Petersen      C.,      Chen      J.,      Rafati      S.,      Louzir   H.,   Muraguchi   A., Wilkins    JA.,    and    Uzonna    JE.    2015.    Identification    of    broadly    conserved    cross-species    protective Leishmania   antigen   and   its   responding   CD4+   T   cells.   Sci   Trans   Med   (PMID:   26491077).             ABSTRACT               FULL TEXT 2 . Okwor,   I.,   Jia,   P.,   and   Uzonna,   J.E.   2015.   Interaction   of   macrophage   antigen-1   (MAC-1)   and   CD40   ligand leads   to   IL-12   production   and   protection   in   CD40   deficient   mice   infected   with   Leishmania   major .   J Immunol. 2015 Aug 24. pii: 1500922 . 3 . Khadem   F.,   Gao   X.,   Mou   Z.,   Jia   P.,   Movassagh   H.,   Onyilagha   C.,   Gounni   AS.,   Wright   MC.,   Uzonna   JE.   2015. Hepatic    stellate    cells    regulate    liver    immunity    to    visceral    leishmaniasis    through    p110δ-dependent induction and expansion of Tregs in mice.  Hepatology. Feb;63(2):620-32 . 4 . Okwor,   I.,   Xu,   G.,   Tang,   H.,   Liang,   Y.,   Fu.,   Y.,   and   Uzonna,   J.E.   2015.   Deficiency   of   CD40   Reveals   an Important Role for LIGHT in Anti-Leishmania Immunity. J. Immunol. 195:191-202 . 5 . Onyilagha   C,   Jia,   P.,   Jayachandran,   N.,   Hou,   S.,   Okwor   I,   Kuriakose   S,   Marshall,   A,   and   Uzonna   J.   2015.   The B   cell   adaptor   molecule   Bam32   is   critically   important   for   optimal   antibody   response   and   resistance   to experimental   Trypanosoma   congolense    infection   in   mice.   PLoS   Negl   Trop   Dis.   Apr   13;9(4):e0003716.   doi: 10.1371/journal.pntd.0003716 . 6 . Li,   J.,   Liu,   D.,   Mou,   Z,   Ihedioha,   O.,   Blanchard,   A.,   Myal   Y.,   and   Uzonna,   J.E.   2015.   Deficiency   of   prolactin- inducible   protein   leads   to   impaired   Th1   immune   response   and   susceptibility   to   Leishmania   major    in mice. Eur J Immunol. 45(4):1082-91 .
2014 1 . Khadem,   F.,   Mou,   Z.,   Liu,   D.,   Varikuti,   S.,   Satoskar,   A.,   and   Uzonna,   J.E.   2014.   Deficiency   of   p110δ   Isoform of   the   Phosphoinositide   3   Kinase   Leads   to   Enhanced   Resistance   to   Leishmania   donovani .   PLoS   Negl   Trop Dis. 2014 Jun 19;8(6):e2951 . 2 . Okwor,   I.,   Jia,   P.,   Mou,   Z.,   Onyilagha,   N.,   and   Uzonna,   J.E.   2014.   CD8 +    T   cells   are   preferentially   activated during   primary   low   dose   Leishmania   major    infection   but   are   completely   dispensable   during   secondary anti-Leishmania immunity. PLoS Negl Trop Dis. 2014 Nov 20;8(11):e3300. doi: 10.1371/ 3 . Mou,   Z.,   Liu   D.,   Okwor,   I.,   Jia,   P.,   Orihara,   K.,   and   Uzonna,   J.E.   2014.   MHC   class   II   restricted   innate-like double   negative   T   cells   contribute   to   optimal   primary   and   secondary   immunity   to   Leishmania   major . PLoS Path. 2014 Sep 18;10(9):e1004396. doi: 10.1371 4 . Okeke,   E.,   Okwor,   I.B.   and   Uzonna,   J.E.   2014.   Regulatory   T   Cells   Restrain   CD4 +    T   Cells   from   Causing Unregulated   Immune   Activation   and   Hypersensitivity   to   Lipopolysaccharide   Challenge.   J   Immunol.   Jul 15;193(2):655-62 . 5 . Kuriakose,   S.,   and   Uzonna,   J.E.   2014.   Diminazene   aceturate   (Berenil),   a   new   use   for   an   old   compound. Int Immunopharmacol. Aug;21(2):342-5 . 6 . Khadem,   F.   and   Uzonna,   J.E.   2014.   Immunity   to   visceral   leishmaniasis:   implications   for   immunotherapy. Future Microbiol 9:901-915 . 7 . Onyilagha   C,   Okwor   I,   Kuriakose   S,   Singh   R,   Uzonna   J.   Low-Dose   Intradermal   Infection   with   Trypanosoma congolense    Leads   to   Expansion   of   Regulatory   T   Cells   and   Enhanced   Susceptibility   to   Reinfection.   Infect Immun. 2014 Mar;82(3):1074-83. doi: 10.1128/IAI.01028-13 .
2013 1 . Liu,   D.,   Mou,   Z.,   Okwor,   I.,   Beverley,   S.,   and   Uzonna,   J.   2013.   Deficiency   of   Leishmania   phosphoglycans   influences   the   magnitude   but   does   not affect the quality of secondary (memory) anti-Leishmania immunity. PLoS One. 11;8(6):e66058. doi: 10.1371/journal.pone.0066058 2 . Kuriakose   S,   Muleme   H,   Onyilagha   C,   Okeke   E,   Uzonna   JE.   2013   Diminazene   aceturate   (Berenil)   modulates   LPS   induced   pro-inflammatory   cytokine production by inhibiting phosphorylation of MAPKs and STAT proteins Innate Immun. 2013 Oct 31. [Epub ahead of print] 3 . Chow   LN,   Choi   KY,   Piyadasa   H,   Bossert   M,   Uzonna   J,   Klonisch   T,   Mookherjee   N.   2013.   Human   cathelicidin   LL-37-derived   peptide   IG-19   confers protection in a murine model of collagen-induced arthritis. Mol Immunol. doi: 10.1016/j.molimm.2013. Epub 2013 Oct 1 4 . Okeke,   E.,   Okwor,   I.B.,   Mou,   Z.,   jia,   P.,   and   Uzonna,   J.E.   2013.   CD4 + CD25 +    Regulatory   T   Cells   Attenuates   LPS-induced   Systemic   Inflammatory Responses and Promotes Survival in Murine Escherichia coli  infection. Shock 40(1):65-73 . 5 . Okwor, I., and Uzonna, J.E. 2013. The immunology of Leishmania/HIV co-infection. Immunol Res. May;56(1):163-71 . 6 . Singh,   R.,   Kone,   B.,   Gounni,   A.S.,   and   Uzonna,   J.E.,   2013;   Molecular   regulation   of   Trypanosoma   congolense -induced   nitric   oxide   production   in macrophages. PLoS One. 2013;8(3):e59631 . 7 . Mou,   Z.,   Muleme,   H.M.,   Liu,   D.,   Jia,   P.,   Okwor,   I.B.,   Kuriakose,   S.,   Beverley,   S.M.,   Uzonna,   J.E.   2013.   Parasite-derived   arginase   influences   secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4 +  T cell exhaustion. J Immunol. 2013 Apr 1;190(7):3380-9 . 8 . Umadat,   V.,   Ihedioha,   O.,   Shiu,   R.,   Uzonna,   J.,   and   Myal,   Y.   2013.   The   prolactin-inducible   protein   (PIP):   a   regulatory   molecule   in   adaptive   and   innate immunity. Open J. Immunol. 4:210-217 .
2012 1 . Okwor,   I.,   Jia,   P.,   Onyilagha,   C.,   Kuriakose,   S.,   and   Uzonna,   J.   2012.   Regulatory   T   cells   enhance   susceptibility   to   experimental   Trypanosoma congolense  infection independent of mouse genetic background. PLoS Neg Trop Dis 6(7). 2 . Kuriakose,   S.,   Muleme,   HM.,   Onyilagha,   C.,   Singh,   R.,   Jia,   P.,   and   Uzonna,   J.E.   2012.   Diminazene   aceturate   (Berenil)   modulates   the   host   cellular   and inflammatory responses to Trypanosoma congolense  infection. PLoS One. 7(11) . 3 . Liu,   D.,   and   Uzonna,   J.E.   2012.   The   early   interaction   of   Leishmania   with   macrophages   and   dendritic   cells   and   its   influence   on   the   host   immune response. Front Cell Infect Microbiol 2:83. 4 . Xie,   J.,   Lotoski,   L.C.,   Chooniedass,   R.,   Su,   R.C.,   Simons,   FE.,   Liem,   J.,   Becker,   A.B.,   Uzonna,   J.,   and   HayGlass,   K.T.   2012.   Elevated   antigen-driven   IL-9 responses are prominent in peanut allergic humans. PLoS One 7(10). 5 . Okwor, I., Mou, Z., Liu, D and Uzonna, J.E. 2012. Protective Immunity and Vaccination Against Cutaneous Leishmaniasis. Front Immunol. 3:128.
2011
2010 1 . Mou,   Z.,   Jia,   P.,   Kuriakose,   S.,   Khadem,   F.,   and   Uzonna,   J.E.      2010.   Interleukin-17-mediated   control   of   parasitemia   in   experimental   Trypanosoma congolense  infection in mice. Infect Immun 78(12):5271-9. 2 . Okwor,   I.,   Kuriakose,   S.,   and   Uzonna,   J.   2010.   Repeated   inoculation   of   killed   Leishmania   major   induces   durable   immune   response   that   protects mice against virulent challenge. Vaccine 33:5451-7. 3 . Liu   D.,   and   Uzonna,   J.E.      2010.   The   p110 d    isoform   of   phosphoinositide   3   kinase   controls   the   quality   of   secondary   anit-Leishmania   immunity   by negatively regulating expansion and effector function of memory T cell subsets. J Immunol. 2010 Mar 15;184(6):3098-105 . 4 . Joyee   A.,   Uzonna,   J.E.,   and   Yang,   X.   2010.   Invariant   NKT   cells   preferentially   modulate   the   function   of   CD8 +    dendritic   cell   subset   in   inducing   type   1 immunity against infection. J. Immunol. 184:2095-106. 5 . Zhou,   G.,   Ma,   Y.,   Jia,   P.,   Guan,   Q.,   Peng,   Z,   and   Uzonna,   J.E.   2010.   Enhancement   of   IL-10   bioactivity   using   an   IL-10   peptide-based   vaccine exacerbates Leishmania major  infection and improves airway inflammation in mice. Vaccine 28:1838-1846.
Articles in Journals (After 2010)
Publications Publications R G
2016 1 . Khadem,   F.,   Jia,   P.,   Mou,   Z.,   Barazandeh,   A.   F.,   Liu,   D.,   Keynan,   Y.,   and   Uzonna,   J.E.   Pharmacological inhibition   of   p110δ   subunit   of   PI3K   confers   protection   against   experimental   leishmaniasis.   Journal   of Antimicrobial Chemotherapy. 2016 . 2 . Ihedioha    OC,    Shiu    RP,    Uzonna    JE,    Myal    Y.    2016    Prolactin-Inducible    Protein:    From    Breast    Cancer Biomarker     to     Immune     Modulator-Novel     Insights     from     Knockout     Mice.     DNA     Cell     Biol.     2016 Oct;35(10):537-541 (PMID: 27602994) . 3 . Okwor   I,   and   Uzonna   JE.   2016.   Pathways   leading   to   interleukin-12   production   and   protective   immunity in cutaneous leishmaniasis. Cell Immunol. 2016 Jun 29 (PMID: 27394077). 4 . Kuriakose   SM,   Singh   R,   and   Uzonna   JE.   2016.   Host   Intracellular   Signaling   Events   and   Pro-inflammatory Cytokine Production in African Trypanosomiasis. Front Immunol. 2016 May 19;7:181. 5 . Okwor   I,   and   Uzonna   J.   2016.   Social   and   Economic   Burden   of   Human   Leishmaniasis.   Am   J   Trop   Med Hyg. 2016 Mar;94(3):489-93. 6 . Okeke   EB,   and   Uzonna   JE.   2016.   In   Search   of   a   Cure   for   Sepsis:   Taming   the   Monster   in   Critical   Care Medicine. J Innate Immun. 2016;8(2):156-70 .
Host-Pathogen  Interaction Laboratory
© 2015 - 2016 Uzonna (Created by F. Khadem)
Articles in Journals (After 2010)

2015

1 . Mou,   Z.,      Li      J.,      Boussoffara      T.,   Kishi   H.,   Hamana   H., Ezzati      P.,      Hu      C.,      Yi      W.,      Liu      D.,      Khadem      F.,      Okwor      I.,     Jia      P.,      Shitaoka   K.,   Wang      S.,      Ndao      M.,   Petersen      C.,     Chen      J.,      Rafati      S.,      Louzir   H.,   Muraguchi   A.,   Wilkins      JA.,     and          Uzonna          JE.     2015.     Identification     of     broadly conserved   cross-species   protective   Leishmania   antigen and     its     responding     CD4+     T     cells.     Sci     Trans     Med.                  ABSTRACT       FULL TEXT 2 . Okwor,   I.,   Jia,   P.,   and   Uzonna,   J.E.   2015.   Interaction   of macrophage   antigen-1   (MAC-1)   and   CD40   ligand   leads to    IL-12    production    and    protection    in    CD40    deficient mice   infected   with   Leishmania   major .   J   Immunol.   2015 Aug 24. pii: 1500922 . 3 . Khadem    F.,    Gao    X.,    Mou    Z.,    Jia    P.,    Movassagh    H., Onyilagha   C.,   Gounni   AS.,   Wright   MC.,   Uzonna   JE.   2015. Hepatic   stellate   cells   regulate   liver   immunity   to   visceral leishmaniasis   through   p110δ-dependent   induction   and expansion   of   Tregs   in   mice.      Hepatology.   Aug   20.   doi: 10.1002/hep.28130. [Epub ahead of print] . 4 . Okwor,   I.,   Xu,   G.,   Tang,   H.,   Liang,   Y.,   Fu.,   Y.,   and   Uzonna, J.E.   2015.   Deficiency   of   CD40   Reveals   an   Important   Role for    LIGHT    in    Anti-Leishmania    Immunity.    J.    Immunol. 195:191-202 . 5 . Onyilagha   C,   Jia,   P.,   Jayachandran,   N.,   Hou,   S.,   Okwor   I, Kuriakose   S,   Marshall,   A,   and   Uzonna   J.   2015.   The   B   cell adaptor    molecule    Bam32    is    critically    important    for optimal       antibody       response       and       resistance       to experimental   Trypanosoma   congolense    infection   in   mice. PLoS     Negl     Trop     Dis.     Apr     13;9(4):e0003716.     doi: 10.1371/journal.pntd.0003716 . 6 . Li,   J.,   Liu,   D.,   Mou,   Z,   Ihedioha,   O.,   Blanchard,   A.,   Myal   Y., and   Uzonna,   J.E.   2015.   Deficiency   of   prolactin-inducible protein   leads   to   impaired   Th1   immune   response   and susceptibility     to     Leishmania     major      in     mice.     Eur     J Immunol. 45(4):1082-91 .

2011

2014 1 . Khadem,   F.,   Mou,   Z.,   Liu,   D.,   Varikuti,   S.,   Satoskar,   A., and   Uzonna,   J.E.   2014.   Deficiency   of   p110δ   Isoform   of the    Phosphoinositide    3    Kinase    Leads    to    Enhanced Resistance   to   Leishmania   donovani .   PLoS   Negl   Trop   Dis. 2014 Jun 19;8(6):e2951 . 2 . Okwor,   I.,   Jia,   P.,   Mou,   Z.,   Onyilagha,   N.,   and   Uzonna,   J.E. 2014.   CD8 +    T   cells   are   preferentially   activated   during primary   low   dose   Leishmania   major    infection   but   are completely       dispensable       during       secondary       anti- Leishmania   immunity.   PLoS   Negl   Trop   Dis.   2014   Nov 20;8(11):e3300. doi: 10.1371/ 3 . Mou,   Z.,   Liu   D.,   Okwor,   I.,   Jia,   P.,   Orihara,   K.,   and   Uzonna, J.E.    2014.    MHC    class    II    restricted    innate-like    double negative    T    cells    contribute    to    optimal    primary    and secondary   immunity   to   Leishmania   major .   PLoS   Path. 2014 Sep 18;10(9):e1004396. doi: 10.1371 4 . Okeke,   E.,   Okwor,   I.B.   and   Uzonna,   J.E.   2014.   Regulatory T   Cells   Restrain   CD4 +    T   Cells   from   Causing   Unregulated Immune        Activation        and        Hypersensitivity        to Lipopolysaccharide        Challenge.        J        Immunol.        Jul 15;193(2):655-62 . 5 . Kuriakose,     S.,     and     Uzonna,     J.E.     2014.     Diminazene aceturate   (Berenil),   a   new   use   for   an   old   compound.   Int Immunopharmacol. Aug;21(2):342-5 . 6 . Khadem,   F.   and   Uzonna,   J.E.   2014.   Immunity   to   visceral leishmaniasis:   implications   for   immunotherapy.   Future Microbiol 9:901-915 . 7 . Onyilagha   C,   Okwor   I,   Kuriakose   S,   Singh   R,   Uzonna   J. Low-Dose     Intradermal     Infection     with     Trypanosoma congolense    Leads   to   Expansion   of   Regulatory   T   Cells   and Enhanced   Susceptibility   to   Reinfection.   Infect   Immun. 2014 Mar;82(3):1074-83. doi: 10.1128/IAI.01028-13 .
2013 1 . Liu,   D.,   Mou,   Z.,   Okwor,   I.,   Beverley,   S.,   and   Uzonna,   J. 2013.      Deficiency      of      Leishmania      phosphoglycans influences    the    magnitude    but    does    not    affect    the quality       of       secondary       (memory)       anti-Leishmania immunity.         PLoS         One.         11;8(6):e66058.         doi: 10.1371/journal.pone.0066058 2 . Kuriakose   S,   Muleme   H,   Onyilagha   C,   Okeke   E,   Uzonna JE.   2013   Diminazene   aceturate   (Berenil)   modulates   LPS induced     pro-inflammatory     cytokine     production     by inhibiting   phosphorylation   of   MAPKs   and   STAT   proteins Innate Immun. 2013 Oct 31. [Epub ahead of print] 3 . Chow   LN,   Choi   KY,   Piyadasa   H,   Bossert   M,   Uzonna   J, Klonisch   T,   Mookherjee   N.   2013.   Human   cathelicidin   LL- 37-derived   peptide   IG-19   confers   protection   in   a   murine model   of   collagen-induced   arthritis.   Mol   Immunol.   doi: 10.1016/j.molimm.2013. Epub 2013 Oct 1 4 . Okeke,   E.,   Okwor,   I.B.,   Mou,   Z.,   jia,   P.,   and   Uzonna,   J.E. 2013.    CD4 + CD25 +     Regulatory    T    Cells    Attenuates    LPS- induced      Systemic      Inflammatory      Responses      and Promotes   Survival   in   Murine   Escherichia   coli    infection. Shock 40(1):65-73 . 5 . Okwor,   I.,   and   Uzonna,   J.E.   2013.   The   immunology   of Leishmania/HIV          co-infection.          Immunol          Res. May;56(1):163-71 . 6 . Singh,   R.,   Kone,   B.,   Gounni,   A.S.,   and   Uzonna,   J.E.,   2013; Molecular      regulation      of      Trypanosoma      congolense - induced   nitric   oxide   production   in   macrophages.   PLoS One. 2013;8(3):e59631 . 7 . Mou,    Z.,    Muleme,    H.M.,    Liu,    D.,    Jia,    P.,    Okwor,    I.B., Kuriakose,   S.,   Beverley,   S.M.,   Uzonna,   J.E.   2013.   Parasite- derived   arginase   influences   secondary   anti-Leishmania immunity     by     regulating     programmed     cell     death-1- mediated   CD4 +    T   cell   exhaustion.   J   Immunol.   2013   Apr 1;190(7):3380-9 . 8 . Umadat,   V.,   Ihedioha,   O.,   Shiu,   R.,   Uzonna,   J.,   and   Myal, Y.     2013.     The     prolactin-inducible     protein     (PIP):     a regulatory   molecule   in   adaptive   and   innate   immunity. Open J. Immunol. 4:210-217 .
2012 1 . Okwor,    I.,    Jia,    P.,    Onyilagha,    C.,    Kuriakose,    S.,    and Uzonna,      J.      2012.      Regulatory      T      cells      enhance susceptibility    to    experimental    Trypanosoma    congolense   infection    independent    of    mouse    genetic    background. PLoS Neg Trop Dis 6(7). 2 . Kuriakose,   S.,   Muleme,   HM.,   Onyilagha,   C.,   Singh,   R.,   Jia, P.,   and   Uzonna,   J.E.   2012.   Diminazene   aceturate   (Berenil) modulates      the      host      cellular      and      inflammatory responses    to    Trypanosoma    congolense     infection.    PLoS One. 7(11) . 3 . Liu,   D.,   and   Uzonna,   J.E.   2012.   The   early   interaction   of Leishmania   with   macrophages   and   dendritic   cells   and its   influence   on   the   host   immune   response.   Front   Cell Infect Microbiol 2:83. 4 . Xie,   J.,   Lotoski,   L.C.,   Chooniedass,   R.,   Su,   R.C.,   Simons,   FE., Liem,   J.,   Becker,   A.B.,   Uzonna,   J.,   and   HayGlass,   K.T.   2012. Elevated   antigen-driven   IL-9   responses   are   prominent   in peanut allergic humans. PLoS One 7(10). 5 . Okwor,    I.,    Mou,    Z.,    Liu,    D    and    Uzonna,    J.E.    2012. Protective   Immunity   and   Vaccination   Against   Cutaneous Leishmaniasis. Front Immunol. 3:128.
2010 1 . Mou,   Z.,   Jia,   P.,   Kuriakose,   S.,   Khadem,   F.,   and   Uzonna,   J.E.     2010.   Interleukin-17-mediated   control   of   parasitemia   in experimental   Trypanosoma   congolense    infection   in   mice. Infect Immun 78(12):5271-9. 2 . Okwor,   I.,   Kuriakose,   S.,   and   Uzonna,   J.   2010.   Repeated inoculation   of   killed   Leishmania   major   induces   durable immune    response    that    protects    mice    against    virulent challenge. Vaccine 33:5451-7. 3 . Liu   D.,   and   Uzonna,   J.E.      2010.   The   p110 d    isoform   of phosphoinositide     3     kinase     controls     the     quality     of secondary     anit-Leishmania     immunity     by     negatively regulating   expansion   and   effector   function   of   memory   T cell subsets. J Immunol. 2010 Mar 15;184(6):3098-105 . 4 . Joyee   A.,   Uzonna,   J.E.,   and   Yang,   X.   2010.   Invariant   NKT cells     preferentially     modulate     the     function     of     CD8 +   dendritic   cell   subset   in   inducing   type   1   immunity   against infection. J. Immunol. 184:2095-106. 5 . Zhou,   G.,   Ma,   Y.,   Jia,   P.,   Guan,   Q.,   Peng,   Z,   and   Uzonna, J.E.   2010.   Enhancement   of   IL-10   bioactivity   using   an   IL-10 peptide-based    vaccine    exacerbates    Leishmania    major   infection    and    improves    airway    inflammation    in    mice. Vaccine 28:1838-1846.
R G
2016 1 . Khadem,   F.,   Jia,   P.,   Mou,   Z.,   Barazandeh,   A.   F.,   Liu,   D., Keynan,   Y.,   and   Uzonna,   J.E.   Pharmacological   inhibition of   p110δ   subunit   of   PI3K   confers   protection   against experimental    leishmaniasis.    Journal    of    Antimicrobial Chemotherapy. 2016 . 2 . Ihedioha     OC,     Shiu     RP,     Uzonna     JE,     Myal     Y.     2016 Prolactin-Inducible      Protein:      From      Breast      Cancer Biomarker   to   Immune   Modulator-Novel   Insights   from Knockout   Mice.   DNA   Cell   Biol.   2016   Oct;35(10):537-541 (PMID: 27602994) . 3 . Okwor    I,    and    Uzonna    JE.    2016.    Pathways    leading    to interleukin-12   production   and   protective   immunity   in cutaneous   leishmaniasis.   Cell   Immunol.   2016   Jun   29 (PMID: 27394077). 4 . Kuriakose    SM,    Singh    R,    and    Uzonna    JE.    2016.    Host Intracellular    Signaling    Events    and    Pro-inflammatory Cytokine   Production   in   African   Trypanosomiasis.   Front Immunol. 2016 May 19;7:181. 5 . Okwor    I,    and    Uzonna    J.    2016.    Social    and    Economic Burden   of   Human   Leishmaniasis.   Am   J   Trop   Med   Hyg. 2016 Mar;94(3):489-93. 6 . Okeke   EB,   and   Uzonna   JE.   2016.   In   Search   of   a   Cure   for Sepsis:   Taming   the   Monster   in   Critical   Care   Medicine.   J Innate Immun. 2016;8(2):156-70 .