Host-Pathogen Interaction Laboratory
© 2015 - 2016 Uzonna (Created by F. Khadem)
2009 1 . Okwor,   I   and   Uzonna,   J.   2009.   Immunotherapy   as   a   strategy   for   treatment   of   leishmaniasis:   a   review   of the literature. Immunotherapy 1:765 . 2 . Liu,   D.,   Kebaier,   C.,   Pakpour,   N.,   Capul,   A.,   Beverley,   S.,   Scott,   P,   and   Uzonna,   J.   2009.   Leishmania   major   phosphoglycans   influence   the   host   early   immune   response   by   modulating   dendritic   cell   functions. Infect Immun 77(8):3272-83 . 3 . Okwor,   I.,   Liu,   D.,   Beverley,   S.,   and   Uzonna,   J.         2009.   Inoculation   of   killed   Leishmania   major   into   immune mice rapidly disrupts immunity to a secondary challenge via IL-10-mediated process. PNAS 106:13951 . 4 . Muleme,   H.,   Palfi,   A.,   Azinwi,   R.,   Beverley,   S.,   and   Uzonna,   J.E.   2009.   Infection   of   mice   with   arginase deficient   Leishmania   major    identifies   a   novel   role   of   parasite-derived   arginase   in   disease   pathogenesis independent of host immune response. J. Immunol. 183:8068-76 . 5 . Okwor,   I.,   Liu,   D.,   and   Uzonna,   J.E.   2009.   Qualitative   differences   in   the   early   immune   response   to   live and   killed   Leishmania   major:   Implications   for   vaccination   strategies   against   Leishmaniasis.   Vaccine 28;27(19):2554-62 . 6 . Okwor,   I.,   Muleme,   H.,   Jia,   P.,   and   Uzonna,   J.E.   2009.   Altered   proinflammatory   cytokine   production   and enhanced   resistance   to   Trypanosoma   congolense    infection   in   lymphotoxin   beta-deficient   mice.      J   Infect Dis. 1;200(3):361-9 . 7 . Okwor,    I    and    Uzonna,    J.    2009.    Status    of    vaccines    and    vaccination    strategies    against    cutaneous leishmaniasis. Hum Vacc  5(5):291-301 .
2008 1 . Li,   X.Y.,   Jin,   L.J.,   Uzonna,   J.E.,   Li,   S.Y.,   Liu,   J.J.,   Li,   H.Q.,   Lu,   Y.N.,   Zhen,   Y.H.,   Xu,   Y.P.   2008.   Chitosan-alginate microcapsules   for   oral   delivery   of   egg   yolk   immunoglobulin   (IgY):   In   vivo   evaluation   in   a   pig   model   of enteric colibacillosis. Vet Immunol Immunopathol 129:132 . 2 . Okwor,     I     and     Uzonna,     J.     2008.     Persistent     parasites     and     immunologic     memory     in     cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies. Immunol Res 41:123-136 .
2007 1 . Xu   G.,   Liu,   D.,   Fan,   Y.,   Yang,   X,   Korner,   H.,   Fu,   YX   and   Uzonna,   J.   2007.   Lymphotoxin   alpha   beta   2 (membrane   lymphotoxin)   is   critically   important   for   resistance   to   Leishmania   major    infection   in   mice.   J Immunol. 179:6901-6909 . 2 . Xu   G.,   Liu,   D.,   Okwor,   I.,   Yang,   W.,   Korner,   H.,   Kung,   S.P.,   Fu,   YX.,   and   Uzonna,   J.      2007.   LIGHT   is   critical   for IL-12   production   by   dendritic   cells,   CD4 +    Th1   development   and   resistance   to   L.   major .   J.   Immunol. 179:5358-5366 .
2006 1 . Kebaier   C,   J.E.   Uzonna,   S.M.   Beverley,   and   P.   Scott.   2006.   Immunization   with   persistent   attenuated   Delta   lpg2   Leishmania   major    parasites   requires adjuvant to provide immunity in C57BL/6 mice. Infect Immun 74:777-780 . 2 . Strutt,   T.,   J.E.   Uzonna,   K.   McKinstry,   and   P.   Bretscher.   2006.   Activation   of   thymic   T   cells   by   MHC   alloantigens   requires   allo-MHC   bearing   B   cells.   Int Immunol. 18:719-728 .
2004 1 . Uzonna,   J.E.,   C.   Zaph,   and   P.   Scott.   2004.   Central   memory   T   cells   mediate   long-term   immunity   to   Leishmania   major   in   the   absence   of   persistent parasites. Nat Med 4: 1104-1110 . (C Zaph and J Uzonna contributed equally to this manuscript and are co-first authors). 2 . Uzonna,   J.E.,   K.   Joyce,   and   P.   Scott.   2004.   Low   dose   Leishmania   major    promotes   a   transient   Th2   response   that   is   downregulated   by   IFN- g -producing CD8+ T cells. J Exp Med. 199:1559-1566 . 3 . Uzonna,   J.E.,   G.   Spath,   S.M.   Beverley,   and   P.   Scott.   2004.   Vaccination   with   phosphoglycan-deficient   Leishmania   major    protects   highly   susceptible mice from virulent challenge without inducing a strong Th1 response. J. Immunol. 172:3793-3797 . 4 . Scott,   P.,   D   Artis,   J.   Uzonna,   and   C.   Zaph.   2004.   The   development   of   effector   and   memory   T   cells   in   cutaneous   Leishmaniasis:   the   implications   for vaccine development. Immunol Rev 201:318-338 .
2005 1 . Sweeney,   R.,   J.   Uzonna,   R.H.   Whitlock,   P.   Chilton,   and   P.   Scott.   2005.   Tissue   predilection   and   effect   of   dose   on   Mycobacterium   avium    subs. Paratuberculosis organism recovery in a bovine experimental infection model. Res Vet Sci. 80:253-259 .
Articles in Journals (Before 2010)
2000 - 2003 1. To view 2003 publications click here. 2. To view 2002 publications click here. 3. To view 2001 publications click here. 4. To view 2000 publications click here.
1997 - 1999 1. To view 1999 publications click here. 2. To view 1998 publications click here. 3. To view 1997 publications click here.
Publications Publications R G
Host-Pathogen  Interaction Laboratory
© 2015 - 2016 Uzonna (Created by F. Khadem)
Articles in Journals (Before 2010)

Before 2004

1. To view 2003 publications click here. 2. To view 2002 publications click here. 3. To view 2001 publications click here. 4. To view 2000 publications click here. 5. To view 1999 publications click here. 6. To view 1998 publications click here. 7. To view 1997 publications click here.
2009 1 . Okwor,    I    and    Uzonna,    J.    2009.    Immunotherapy    as    a strategy   for   treatment   of   leishmaniasis:   a   review   of   the literature. Immunotherapy 1:765 . 2 . Liu,   D.,   Kebaier,   C.,   Pakpour,   N.,   Capul,   A.,   Beverley,   S., Scott,     P,     and     Uzonna,     J.     2009.     Leishmania     major   phosphoglycans     influence     the     host     early     immune response   by   modulating   dendritic   cell   functions.   Infect Immun 77(8):3272-83 . 3 . Okwor,   I.,   Liu,   D.,   Beverley,   S.,   and   Uzonna,   J.         2009. Inoculation    of    killed    Leishmania    major    into    immune mice     rapidly     disrupts     immunity     to     a     secondary challenge via IL-10-mediated process. PNAS 106:13951 . 4 . Muleme,    H.,    Palfi,    A.,    Azinwi,    R.,    Beverley,    S.,    and Uzonna,    J.E.    2009.    Infection    of    mice    with    arginase deficient    Leishmania    major     identifies    a    novel    role    of parasite-derived     arginase     in     disease     pathogenesis independent    of    host    immune    response.    J.    Immunol. 183:8068-76 . 5 . Okwor,    I.,    Liu,    D.,    and    Uzonna,    J.E.    2009.    Qualitative differences   in   the   early   immune   response   to   live   and killed    Leishmania    major:    Implications    for    vaccination strategies           against           Leishmaniasis.           Vaccine 28;27(19):2554-62 . 6 . Okwor,   I.,   Muleme,   H.,   Jia,   P.,   and   Uzonna,   J.E.   2009. Altered     proinflammatory     cytokine     production     and enhanced      resistance      to      Trypanosoma      congolense   infection   in   lymphotoxin   beta-deficient   mice.      J   Infect Dis. 1;200(3):361-9 . 7 . Okwor,   I   and   Uzonna,   J.   2009.   Status   of   vaccines   and vaccination   strategies   against   cutaneous   leishmaniasis. Hum Vacc  5(5):291-301 .
2008 1 . Li,   X.Y.,   Jin,   L.J.,   Uzonna,   J.E.,   Li,   S.Y.,   Liu,   J.J.,   Li,   H.Q.,   Lu, Y.N.,     Zhen,     Y.H.,     Xu,     Y.P.     2008.     Chitosan-alginate microcapsules       for       oral       delivery       of       egg       yolk immunoglobulin   (IgY):   In   vivo   evaluation   in   a   pig   model of    enteric    colibacillosis.    Vet    Immunol    Immunopathol 129:132 . 2 . Okwor,   I   and   Uzonna,   J.   2008.   Persistent   parasites   and immunologic     memory     in     cutaneous     leishmaniasis: implications     for     vaccine     designs     and     vaccination strategies. Immunol Res 41:123-136 .
2007 1 . Xu   G.,   Liu,   D.,   Fan,   Y.,   Yang,   X,   Korner,   H.,   Fu,   YX   and Uzonna,   J.   2007.   Lymphotoxin   alpha   beta   2   (membrane lymphotoxin)    is    critically    important    for    resistance    to Leishmania     major      infection     in     mice.     J     Immunol. 179:6901-6909 . 2 . Xu   G.,   Liu,   D.,   Okwor,   I.,   Yang,   W.,   Korner,   H.,   Kung,   S.P., Fu,   YX.,   and   Uzonna,   J.      2007.   LIGHT   is   critical   for   IL-12 production    by    dendritic    cells,    CD4 +     Th1    development and resistance to L. major . J. Immunol. 179:5358-5366 .
2006 1 . Kebaier   C,   J.E.   Uzonna,   S.M.   Beverley,   and   P.   Scott.   2006. Immunization    with    persistent    attenuated    Delta    lpg2 Leishmania   major    parasites   requires   adjuvant   to   provide immunity in C57BL/6 mice. Infect Immun 74:777-780 . 2 . Strutt,    T.,    J.E.    Uzonna,    K.    McKinstry,    and    P.    Bretscher. 2006.   Activation   of   thymic   T   cells   by   MHC   alloantigens requires   allo-MHC   bearing   B   cells.   Int   Immunol.   18:719- 728 .
2004 1 . Uzonna,    J.E.,    C.    Zaph,    and    P.    Scott.    2004.    Central memory     T     cells     mediate     long-term     immunity     to Leishmania   major   in   the   absence   of   persistent   parasites. Nat     Med     4:     1104-1110 .     (C     Zaph     and     J     Uzonna contributed   equally   to   this   manuscript   and   are   co-first authors). 2 . Uzonna,    J.E.,    K.    Joyce,    and    P.    Scott.    2004.    Low    dose Leishmania    major     promotes    a    transient    Th2    response that   is   downregulated   by   IFN- g -producing   CD8+   T   cells.   J Exp Med. 199:1559-1566 . 3 . Uzonna,   J.E.,   G.   Spath,   S.M.   Beverley,   and   P.   Scott.   2004. Vaccination    with    phosphoglycan-deficient    Leishmania major     protects    highly    susceptible    mice    from    virulent challenge    without    inducing    a    strong    Th1    response.    J. Immunol. 172:3793-3797 . 4 . Scott,    P.,    D    Artis,    J.    Uzonna,    and    C.    Zaph.    2004.    The development     of     effector     and     memory     T     cells     in cutaneous   Leishmaniasis:   the   implications   for   vaccine development. Immunol Rev 201:318-338 .
2005 1 . Sweeney,   R.,   J.   Uzonna,   R.H.   Whitlock,   P.   Chilton,   and   P. Scott.   2005.   Tissue   predilection   and   effect   of   dose   on Mycobacterium   avium    subs.   Paratuberculosis   organism recovery   in   a   bovine   experimental   infection   model.   Res Vet Sci. 80:253-259 .
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